“SYNTHESIS, CHRACTERIZATION AND EVALUTION OF ANTIMICROBIAL EFFECT OF CHITOSAN CONJUGATED SILVERNANOPARTICLES AGAINST PATHOGENIC BACTERIA AND THEIR BIOMEDICAL APPLICATION ’’.

The study is aimed to determine the antimicrobial evaluation of chitosan conjugated silver nanoparticles againist pathogenic bacteria. Pathogenic bacteria samples were collected from SMS hospital and then subjected to identification of bacteria according to their m characterstics and morphology. Chitosan conjugated silver nanoparticles synthesized by adding NaOH and AgNo3 solution to chitosan solution at 45ºc and were characterized by UV, SEM, TEM and FTIR. The antimicrobial activity was determined by kirbuy stokes method. Antibacterial effect of chitosan-silver nanoparticle was increased by increasing the concentration of the (ch-AgNPs). The presence of small concentration of silver nanoparticles in the composite was enough to significantly enhance antibacterial activity.