SYNTHESIS, CHARACTERIZATION, ANTI-INFLAMMATORY, ANTIMICROBIAL AND DNA BINDING PROPERTIES OF Co(II). Ni(II), Cd(II) AND Cu(II) COMPLEXES WITH SCHIFF BASE.

Asha M S; Othbert Pinto; Nagendra Murthy V N; Varadha Raj; Delarasoltanesmaeili.

doi:10.21474/IJAR01/1305

31 Aug 2016 Vol. 4 (08) pp. 1065-1074 DOI: 10.21474/IJAR01/1305

SYNTHESIS, CHARACTERIZATION, ANTI-INFLAMMATORY, ANTIMICROBIAL AND DNA BINDING PROPERTIES OF Co(II). Ni(II), Cd(II) AND Cu(II) COMPLEXES WITH SCHIFF BASE.

Asha M S, Othbert Pinto, Nagendra Murthy V N, Varadha Raj and Delarasoltanesmaeili.

St. Philomena’s College, Bannimantap, Mysore, Karnataka, India.
Department of Studies in Biotechnology, JSS College of Arts, Commerce and Science, Ooty road, Mysore, Karnataka, India.

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Abstract

The meal complexes of Co(II), Ni(II), Cu(II), Cd(II) and Zn(II) derived from hydroxyl benzophenone and o-phenylenediamine have been synthesised and characterized by elemental analysis, 1H NMR, FT-IR, UV-visible, Mass spectroscopy, molar conductometry, magnetic susceptibility and thermal analysis study. The FT-IR spectral study reveals that the ligand behaves as a dibasic tetradentate ligand with N2O2 donor atoms sequence towards central metal ion. The physico-chemical study reveals octahedral geometry for the complexes. The results show the formation of 2:1(ligand: metal chloride) complexes with amine and screened for anti-inflammatory, antimicrobial, DNA binding properties.

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How to Cite This Article

Asha M S , Othbert Pinto, Nagendra Murthy V N, Varadha Raj and Delarasoltanesmaeili. (2016); SYNTHESIS, CHARACTERIZATION, ANTI-INFLAMMATORY, ANTIMICROBIAL AND DNA BINDING PROPERTIES OF Co(II). Ni(II), Cd(II) AND Cu(II) COMPLEXES WITH SCHIFF BASE., International Journal of Advanced Research (IJAR), 4 (08), 1065-1074, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/1305