Vol. 4 (09) pp. 1802-1813 DOI: 10.21474/IJAR01/1657

CLINICAL AND MORPHOLOGICAL CHARACTERISTICS OF NSCLC AND VEGF GENE POLYMORPHISM.

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  • Belarusian State Medical University, Minsk, Republic of Belarus.
  • Institute of Genetics and Cytology NAS of Belarus, Minsk, Republic of Belarus,
  • City Clinical Pathologoanatomic Bureau, Minsk, Republic of Belarus.
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Abstract

Our study shown prognostic effect of VEGF gene polymorphisms on clinical features of NSCLC. As vascular endothelial growth factor (VEGF) is a major driver of angiogenesis and cancer cells proliferation, we evaluated survival the group of patients with NSCLC from the position of VEGF gene polymorphisms, TNM and histological types of tumor. Analysis revealed that polymorphisms VEGF gene influence the outcome of treatment, histological type, size, metastasis as aggressiveness of the NSCLC.

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How to Cite This Article

Mikhail N. Shapetska, Anna N. Shchayuk, Elena P. Mikhalenko, Natalia V. Chebotareva, Svetlana N. Pisarchik and Evelina V. Krupnova. (2016); CLINICAL AND MORPHOLOGICAL CHARACTERISTICS OF NSCLC AND VEGF GENE POLYMORPHISM., Int. J. of Adv. Res., 4 (09), 1802-1813, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/1657

Corresponding Author

Mikhail N. Shapetska

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