EVALUATION OF LIVER AND RENAL FUNCTION TESTS IN ? – THALASSEMIA MAJOR PATIENTS IN MISSAN PROVINCE.

This study was planned to evaluated some function tests in liver and renal in patients with thalassemia by measuring aspartate aminotransferas ( AST ) , alanine aminotransferas ( ALT ) , bilirubin, urea , creatinine , glucose and feeritin. This study was carried out in center of blood diseases and tumors in Missan province. 50 patients with ?- thalassemia (23male and 27 female) were included in this study. Their ages ranged between 2- 21 year. 50 matched normal individuals were taken as control group. In the present study AST and ALT were significantly decrease in ?- thalassemia patients than in the control (p<0.05). creatinine and ferritin were significantly higher in ?- thalassemia patients than in control group (p<0.01). The mean values of other parameters including bilirubin, urea and glucose were found to be unchanged.