Vol. 5 (03) pp. 1354-1361 DOI: 10.21474/IJAR01/3643

KINETICS AND MECHANISM OF THE HYDROLYSIS OF 4-HYDROXYBIPHENYL PHOSPHATE MONOESTER.

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  • Cadila Pharmaceutical, Ahmedabad.
  • Christ Church College, Kanpur.
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Abstract

Hydrolysis of 4-hydroxybiphenyl phosphate monoester has been carried out in acid (HCl) Solution at 97± 0.50 C and the inorganic phosphate obtained during hydrolysis has been estimated coloremetrically . Pseudo first order rate coefficients have been calculated neutral and conjucated acid species have been found to be reactive and contributed to the overall hydrolysis in the acid region. The calculated rate coefficients are in good agreement with the experimentally observed ones. The effect of temperature, solvent and substrate concentration on the rate of hydrolysis have been studied. The results suggest that the hydrolysis of monoester occurs by the cleavage of P-O bond fission.

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How to Cite This Article

Ruchi Singh And Shweta Chand. (2017); KINETICS AND MECHANISM OF THE HYDROLYSIS OF 4-HYDROXYBIPHENYL PHOSPHATE MONOESTER., Int. J. of Adv. Res., 5 (03), 1354-1361, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/3643

Corresponding Author

Dr. Shweta Chand
Asstt. Professor, Christ Church College Kanpur
Creative Commons Attribution 4.0 This work is licensed under a Creative Commons Attribution 4.0 International License.