A GREEN SYNTHESIS AND BIOLOGICAL STUDIES OF NOVEL N-(SUBSTITUTED-BENZYLIDENE)-4-(5-(4-CHLOROPHENYL)-1-PHENYL-4, 5-DIHYDRO-1H-PYRAZOL-3-YL) ANILINE.
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Abstract
Green synthesis of novel schiff base compounds bearing 2-pyrazoline moiety and their biological activities have been described. All the products were obtained in very good yield within 5-10 mins by using grinding method. The structures were confirmed with the help of various spectral studies and observed very good inhibition zone against tested bacterial strains.
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References
- Cimerman, S. Miljani? c, and N. Gali C.; (2000) CroaticaChemicaActa, 73, 81?95
- Schiff, Justus Liebigs (1864) Annalen der Chemie, 131, 118?119
- N. Dhar and C. L. Taploo, (1982) Journal of Scientific and Industrial Research, 41, 501?506
- Ashraf M. ,? Mahmood? K.,? Wajid? A.; (2011) IPCBEE, 10, 1?7
- Jarrahpour, D. Khalili, E. De Clercq, C. Salmi, and J.M. Brunel, (2007) Molecules, 12, 1720?1730
- Khushal M. Kapadiya*, Dipti H. Namera, Kishor M. Kavadia, Ranjan C. Khunt.; (2014) International Letters of Chemistry, Physics and Astronomy, 11(3), 223-232
- Mounika,B.Anupama,J.Pragathi, and C.Gyanakumari.; (2010)
- Journal of Scientific Research, 2, 513?524? Venkatesh.; (2011) Asian Journal of Pharmaceutical and Health Sciences, 1, 8?11 (2011)
- S.Sathe,E.Jaychandran,V.A.Jagtap,andG.M.Sreenivasa.; (2011) International Journal of Pharmaceutical Research and Development, 3, 164?169
- M. Sondhi, N. Singh, A. Kumar, O. Lozach, and L. Meijer., (2006) Bioorganic and Medicinal Chemistry, 14, 3758?3765
- Pandey,D.Dewangan,S.Verma,A.Mishra,andR.D.Dubey.; (2011) International Journal of Chem Tech Research, 3,.178?184
- Chandramouli, M. R. Shivanand, T. B. Nayanbhai, B. Bheemachari, and R. H. Udupi., (2012) Journal of Chemical and Pharmaceutical Research, 4, 1151?1159
- P. Chinnasamy, R. Sundararajan, and S. Govindaraj, (2010) Journal of Advanced Pharmaceutical Technology and Research, 1, 342?347
- M. M. Ali, M. AbulKalam Azad, M. Jesmin et al., (2012) Asian Pacific Journal of Tropical Biomedicine, 2, 438?442
- Miri, N. Razzaghi-asl, and M. K. Mohammadi, (2013) Journal of Molecular Modeling, 19, 727?735
- M. M. Ali, M. AbulKalam Azad, M. Jesmin et al., (2012) Asian Pacific Journal of Tropical Biomedicine, 2, 438?442
- Wei,N.Li,G.Lu,andK.Yao.; (2006) Science in China B, 49, 225?229
- G.Avaji,C.H.VinodKumar,S.A.Patil,K.N.Shivananda, and C. Nagaraju, (2009) European Journal of Medicinal Chemistry, 44, 3552?3559
- N. Venugopala and B. S. Jayashree, (2003) nIndian Journal of Heterocyclic Chemistry, 12, 307?310
- Kumar S., Dhar D. N., Saxena P. N.; (2009) Sci. Ind. Res., 68, 181?187
- Yang X., Wang Q., Huang Y., Fu P., Zhang J., Zeng R.; (2012) Chem. Comm., 25, 55?59
- Shaharyar, M.; Siddiqui, A.A.; Ali, M.A.; Sriram, D.andYogeeswari, P.; (2006) Med. Chem. Lett., 16, 3947-3949
- E. Khadsan, M. V. Kadu, N. H. Aloolkar, (2005) Asian J. Chem., 17(3), 1600
- S. Jolly, G. D. Arora, P. Talwar, (1990) J. Indian Chem. Soc., 67, 1001
- Nugent, R.A.; Murphy, M.; Schlachter, S.T.; Dunn, C.J.; Smith, R.J.; Staite, N.D.; Galinet., Richard, K.A., and Rohloff, N.A.,(1993) Med. Chem. 36, 134-139
- Manna, F.; Chimenti, F.; Bolasco, A.; Cenicola, M.L.; D?Amico, M.; Parrillo, C.; Rossi, F. and Marmo, E. (1992) J. Med. Chem., 27, 633-639
- Babu K., PitchaiP.andGengan R. M;(2015) Chem. Pharm. Res., 7(12), 275-278
- Babu, D. Selvi and P. Pitchai; (2015) Der PharmaChemica, 7(10), 89-92
- Babu and K.Tharini.; (2017) Asian Journal of Chemistry.; 29, 187-190
- Babu, (2018) Asian J. Research Chem. 11(2) 319-328
How to Cite This Article
K. Babu. (2018); A GREEN SYNTHESIS AND BIOLOGICAL STUDIES OF NOVEL N-(SUBSTITUTED-BENZYLIDENE)-4-(5-(4-CHLOROPHENYL)-1-PHENYL-4, 5-DIHYDRO-1H-PYRAZOL-3-YL) ANILINE., Int. J. of Adv. Res., 6 (05), 784-792, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/7096
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