DOCKING STUDIES OF BCL-2 WITH HEMIDESMUS WALLICHII COMPOUNDS FOR ANTI-CANCER STUDIES
- Department of Biotechnology, Koneru Lakshmaiah Education Foundation, Guntur, Andhra Pradesh, India.
Abstract
Medicinal plants have wide spread properties due to the presence of phytocompounds and are the alternative medicines available for thosewho cannot be helped by conventional medicine. In this work we have selected bioactive compounds from Hemidesmus wallichii medicinal plant extracts.Gas chromatography and Mass Spectrum studies were studied to identify the compounds present in the ethanolic extracts based on the retention time and area. The identified compounds were used for anti-cancer activity by insilico method with BCL-2 which plays prominent role in causing cancer. Out of twentyselected compounds, docking results showedMethyl-1-Cyclo Hexane carboxylate and1,2-diacetoxy-5-idohexane as best docked to the BCL-2.
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Kavya Sri Arumilli, Roshni Mocharla, Likhita Ventrapragada, Thelma Aradhya Mudda, Chaturya Ankamma Pamarthi and Himavarshini Kadiyala (2021); DOCKING STUDIES OF BCL-2 WITH HEMIDESMUS WALLICHII COMPOUNDS FOR ANTI-CANCER STUDIES, International Journal of Advanced Research (IJAR), 9 (01), 35-39, ISSN 2320-5407.
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