DOCKING STUDIES OF BCL-2 WITH COSMOSTIGMACORDATUMCOMPUNDS FOR ANTI-CANCER STUDIES
- Department of Biotechnology, Koneru Lakshmaiah Education Foundation, Guntur, Andhra Pradesh, India.
- Department of Molecular Biology, Cresent Biosciences, ICRAB Campus, Kanpur, Uttar Pradesh, India.
Abstract
Medicinal plants have wide spread properties due to the presence of phytocompounds and are the alternative medicines available for thosewho cannot be helped by conventional medicine. In this work we have selected bioactive compounds from Cosmostigmacordatummedicinal plant extracts. Docked compounds were used for anti-cancer activity by insilico method with BCL-2 which plays prominent role in causing cancer. Out of twentyselected compounds, docking results showedMethyl-1-Cyclo Hexane carboxylate and1,2-diacetoxy-5-idohexane as best docked to the BCL-2.
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How to Cite This Article
Sravya Jasthi, Tejasri Abburu, Sai Sree Thanay Allam, Geya Govind, Nandini Ravula, Manas Tripurana and Reethika Singh Ranwas (2023); DOCKING STUDIES OF BCL-2 WITH COSMOSTIGMACORDATUMCOMPUNDS FOR ANTI-CANCER STUDIES, Int. J. of Adv. Res., 11 (07), 271-275, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/17228
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