ACTIVITES ANTIFONGIQUE ET ANTIBACTERIENNE DES EXTRAITS DE FEUILLES DESTYLOSANTHES ERECTABeau
- Laboratoire de BiochimiedeSubstances Naturelles (LBASNa)Faculte des sciences et Techniques, (FST), Universite des Sciences des Techniques et des Technologies de Bamako,(USTTB) Mali.
- Laboratoire de Biochimie Alimentaire, lInstitut des Sciences Appliquees(ISA),Universite des Sciences des Techniques et des Technologies de Bamako,5USTTB), Mali.
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During this work, phytochemical analyzes were carried out on the powder of the leaves of Stylosanthes erecta P. Beauv., as well as qualitative analyzes by thin layer chromatography(TLC) and evaluations. The antifungal and the antibacterial activities of the aqueous extracts were made respectively by the diffusion method and by the dilution method.The TLC revealed the spots including gallic tannins, catechism tannins and flavonoids.The antifungal activity against Candida albicans is proportional to the increase in the concentration of the extracts of total tannins. Concentrations of 1000 Âµg/mL and 1500 Âµg/mL showed complete inhibition of fungal density. Maceration extracts have more antifungal activity than decoction ones. As for the antibacterial activity, Streptococcus ss and N. gonorrhea were more sensitive to thecrude and tannin extracts than flavonoids ones. The largest inhibition diameters were 15 Â± 0.05 mm and 16 Â± 0.04 mm on clinical strains. S. typhi was more sensitive to flavonoid extracts. The minimum inhibitory concentration was around 0.5 mg / mL on E. coli, S. typhi, Streptococcus and N. gonorrhea.
[Singou Keita, Mamadou A. Konare, Meminata Diakite, Moriba Doumbia, Issiaka Togola and Nouhoum Diarra (2023); ACTIVITES ANTIFONGIQUE ET ANTIBACTERIENNE DES EXTRAITS DE FEUILLES DESTYLOSANTHES ERECTABeau Int. J. of Adv. Res. 11 (Feb). 789-799] (ISSN 2320-5407). www.journalijar.com
Laboratoire de biochimie VÃ©gÃ©tale Alimentaire de Biotechnologie (LBVA-B) de la FacultÃ© des sciences et Techniques, UniversitÃ© des Sciences des Techniques et des Technologie de Bamako, Mali. Correspondance, courriel : Singou1keit@gmail.com.
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