Vol. 14 (01) pp. 1431-1433 DOI: 10.21474/IJAR01/22678

MECHANISTIC STUDY OF MELATONIN: A SYSTEMATIC REVIEW

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  • Department of Physiology, Faculty of Basic Medical Sciences,College of Health Sciences, Usmanu Dan fodiyo University, Sokoto, Nigeria.
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Abstract

Background: Melatonin, a neurohormone synthesized primarily in the pineal gland, plays a central role in regulating circadian rhythms and sleep-wake cycles.

Purpose: Beyond its chronobiotic functions,melatonin exhibits potent a ntioxidant,anti inflammatory, immunomodulatory,and oncostatic proper ties.This review explores the multifaceted molecular and cellular mecha nisms of melatonin across physiological and pathological conditions.

Methods: A systematic review following PRISMA guidelines was conducted using databases including PubMed, Scopus, Web of Science, and Google Scholar. Studies from 1990 to 2024 focusing on mechanisti c insights were included.

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How to Cite This Article

B. Aliyu, N.S. Kangiwa and U.Z. Umar (2026); MECHANISTIC STUDY OF MELATONIN: A SYSTEMATIC REVIEW, Int. J. of Adv. Res., 14 (01), 1431-1433, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/22678

Corresponding Author

Aliyu Buhari
Usmanu Danfodiyo University, Sokoto, Nigeria
Nigeria
Creative Commons Attribution 4.0 This work is licensed under a Creative Commons Attribution 4.0 International License.