EFFECT OF SHODHITA SHILAJATU AND RAJATA BHASMA ON ANXIETY - A VITRO STUDY

Background: Shilajatu and Rajata are important mineral drugs having medhya property. There are studies available on effect of shilajatu on diabetes, obesity and anxiety also, Rajata bhasma have proven to increase the memory, concentration. The main objective of the study was to observe the effect of Shodhita Shilajatu and Rajata Bhasma on anxiety in mice. Methods: Shodhana of Shilajatu was carried out by suryatapi method/, Shodhana of Rajata was carried out according to classical texts by using taila,takra,gomutra, kanji, kulattha kwatha. Rajata Bhasma was prepared using Kumari swarasa Bhavana as per Ayurveda Prakasha. Organoleptic characteristics, ash value analysis, SEM analysis of Rajata and Shilajatu were carried out according to standards. Anti Anxiety activity was analyzed by using light and dark test, open and closed arm activity test on four group of mice