SYNTHESIS OF NOVEL THIAZOLIDINONES AND THEIR BIOLOGICAL ACTIVITIES

NOOSRAT KORTIWALA; JITESH PATEL; VIKAS DESAI

30 Sep 2015 Vol. 3 (09) pp. 971-976

SYNTHESIS OF NOVEL THIAZOLIDINONES AND THEIR BIOLOGICAL ACTIVITIES

NOOSRAT KORTIWALA, JITESH PATEL and VIKAS DESAI

Department of Chemistry, B.K.M. Science College, Valsad, 396001, Gujarat (India)

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Abstract

Various Novel 2-(Substitutedphenyl) -3-(2-(1-hydroxycyclohexyl)-2-(4-methoxyphenyl) ethyl)-2-phenylthiazolidin-4-one (2b) were prepared by refluxing with Schiff bases (2a) in presence of thioglycolic acid in benzene. The Schiff bases were prepared by condensation of various Aryl Aldehydes with 1-[2-amino-1-(3-methoxyphenyl)ethyl]cyclohexanol. The titled Compounds were characterized by TLC and spectral analysis. Some of the synthesized compounds showed potential antibacterial and antifungal activity.

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How to Cite This Article

NOOSRAT KORTIWALA, JITESH PATEL AND VIKAS DESAI (2015); SYNTHESIS OF NOVEL THIAZOLIDINONES AND THEIR BIOLOGICAL ACTIVITIES, International Journal of Advanced Research (IJAR), 3 (09), 971-976, ISSN 2320-5407.