An in silico based characterization and analysis of A Disintegrin MetalloProteinase with Thrombospodin Motifs (ADAMTS) in Homo Sapiens with respect to Angiognesis and/or Cancer

Rahul Ravichandran; Riya Rane

30 Nov 2015 Vol. 3 (11) pp. 841- 852

An in silico based characterization and analysis of A Disintegrin MetalloProteinase with Thrombospodin Motifs (ADAMTS) in Homo Sapiens with respect to Angiognesis and/or Cancer

Rahul Ravichandran, Riya Rane

D.Y.Patil University, School of Biotechnology and Bioinformatics.

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Abstract

A Disintegrin MetalloProteinase with Thrombospodin Motifs (ADAMTS) belongs to the family of peptidase. 19 members of ADAMTS family are identified in humans. They play a role in enzyme activities.Out of the 19 ADAMTS present in humans 10 are found to be involved in Angiogenesis and/or cancer.ADAMTS8 is antiangiogenic. The following study deals with analysis of ADAMTS identified in humans. The ADAMTS having disease causing potential; were studied in detail. The identification of their domains and disordered regions was done using various bio-computational tools.

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How to Cite This Article

Rahul Ravichandran, Riya Rane (2015); An in silico based characterization and analysis of A Disintegrin MetalloProteinase with Thrombospodin Motifs (ADAMTS) in Homo Sapiens with respect to Angiognesis and/or Cancer, International Journal of Advanced Research (IJAR), 3 (11), 841- 852, ISSN 2320-5407.