Changes in Peripheral Plasma hormone Concentrations and metabolites during the last trimester of pregnancy and around Parturition in the Egyptian Buffalo and Baladi cows.

It is well known that pregnancy and parturition are controlled by reproductive and metabolic hormones. The present work was designed to clarify the relationship between reproductive and metabolic hormones, their metabolic effects and some biochemical parameters in blood of buffaloes and cows. plasma concentrations of progesterone, estrogen, , prolactin, Insulin like growth factor-1 (IGF-1),leptin, cortisol ,triiodothyronine, thyroxin, thyroid stimulating hormone(TSH), Glucose, Total protein , Triglyceride and Cholesterol around parturition were studied on buffalo and cows. Results indicated that, the concentrations of plasma IGF-1, leptin, and, T3, T4 were decrease while cortisol and thyroid stimulating hormone (TSH) were increase with the progress in pregnancy. The concentrations of plasma estrogen and prolactin were increase around parturition, the opposite trend recorded in plasma progesterone levels. The concentrations of plasma glucose and total protein were increase around parturition, the opposite trend recorded in triglyceride and cholesterol levels. Parturition is an important period in buffaloes and cows from the point of view of physiological changes taking place, which in turn produce measurable changes in the diagnostic parameters of the blood.