Multiple basal cell carcinomas developed after radiation therapy for tinea capitis treated by topical podophyllin solution 25% in Iraqi patient

Background: Prior to the introduction of griseofulvin in 1960, (3) the world standard for treatment of tinea capitis was scalp irradiation. (4,5) Occurrence of BCC following radiotherapy for tinea capitis is well-known,1-2 Radiation therapy conveys ?4-fold risk to the development of skin cancer in different reports.(8,9) Podophyllin is an antimitotic and caustic agent. Objective: to test the effectiveness of 25% topical podophyllin solution in treatment multiple BCCs developed after radiation therapy. Methodology and results: 70 year-old farmer male often reported has multiple slowly enlarging crusted lesions on the scalp since 4 years does not heal and that bleeds when traumatized. Patient has a history of radiation exposure for tinea capitis since childhood. These lesions Improve clinically and histological as BCC, treated by 25% topical podophyllin solution weekly for six weeks, All the lesions cured clinically and histological with good cosmetic appearance. Conclusion: 25% topical podophyllin solution is an effective therapy for these multiple basal cell carcinomas with good cosmetic appearance.