Vol. 5 (05) pp. 687-694 DOI: 10.21474/IJAR01/4166

CLINICAL AND MRI ASSESSMENT OF THE PAROTID GLAND IN DIABETIC PATIENTS: PRELIMINARY STUDY.

  • Assistant Lecturer of Oral and Maxillofacial Radiology, Faculty of Oral and Dental Medicine, Cairo University.
  • Professor of Oral and Maxillofacial Radiology, Faculty of Oral and Dental Medicine, Cairo University.
  • Professor of Radiology, Faculty of Medicine, Cairo University
  • Assoc. Professor of Oral and Maxillofacial Radiology, Faculty of Oral and Dental Medicine, Cairo University.
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Abstract

Objective: To assess the parotid gland in diabetic patients clinically and by using magnetic resonance imaging. Methods: 20 subjects (10 volunteers and 10 diabetic patients) were examined clinically to detect the presence of xerostomia and badoral hygiene. Salivary flow ratethen, was measured for all subjects to assess the gland function. Finally, axial and coronal MR-T1WIs were acquired followed by MRsialographyfor the left parotid gland. Results: The diabetic group showed statistically significant higher prevalence of xerostomia andbad oral hygiene than the control group (P-value = 0.001; 0.006respectively). The salivary flow rate of the control group showed statistically significant higher mean values in both the pre- and post-stimulation states(P-values = 0.027; 0.001 respectively) than the diabetic group. The ductal changes in the diabetic group showed statistically significant higher prevalence of ductal changes than the control group (P-value = 0.025). As well, the diabetic group showed statistically significant higher prevalence of enlargement (P-value = 0.001) and statistically significant higher prevalence of parenchymal changes (P-value = 0.019) than the control group Conclusion Diabetes mellitus may cause the hypofunction of the salivary glands and the MRI and MR sialography may be valuable techniques in the examination of the structure and ductal morphology of the salivary glands of diabetic patients.

Keywords

How to Cite This Article

Ola Mohamed Rehan, Hoda Abdel Kader Saleh, Ayman Ismail Kamel and NohaSaleh Abu Taleb. (2017); CLINICAL AND MRI ASSESSMENT OF THE PAROTID GLAND IN DIABETIC PATIENTS: PRELIMINARY STUDY., International Journal of Advanced Research (IJAR), 5 (05), 687-694, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/4166

Corresponding Author

Ola Mohamed Rehan
Assistant Lecturer of Oral and Maxillofacial Radiology, Faculty of Oral and Dental Medicine, Cairo University.

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References

  1. Diabetes mellitus may cause the hypofunction of the salivary glands and the MRI and MR sialography are valuable techniques in the examination of the structure and ductal morphology of the salivary glands.
  2. Wang B, Du J, Zhu Z, Ma Z, Wang S, Shan Z. (2017): Evaluation of Parotid Salivary Glucose Level for Clinical Diagnosis and Monitoring Type 2 Diabetes Mellitus Patients. Biomed Res Int., 1?5.
  3. Malicka B, Kaczmarek U, Skokiewicz-Malinowska K. (2014): Prevalence of xerostomia and the salivary flow rate in diabetic patients. Adv Clin Exp Med., 23(2):225?33.
  4. Bissong MEA, Azodo CC, Agbor MA, Fon PN, Bissong M , Azodo CC , Agbor AM , Nkuo- Akenji T , Nde F . (2015): Oral health Status of diabetic patients in South West. Oral health status of diabetes mellitus patients in Southwest Cameroon.
  5. Kuan EC, Mallen-St. Clair J, St. John MA. (2016): Evaluation of Parotid Lesions. Otolaryngol Clin North Am., 49(2):313?25.
  6. White SC, Pharoah MJ. (2014): Oral Radiology principles and interpretation (7th edn). Canada El Sevier Mosby.
  7. Kalinowski M, Heverhagen JT, Rehberg E, Klose KJ, Wagner HJ. (2002): Comparative study of MR sialography and digital subtraction sialography for benign salivary gland disorders. Am J Neuroradiol., 23(9):1485?92.
  8. Diogo L?fgren C, Wickstr?m C, Sonesson M, Tapia Lagunas P, Christersson C. (2012): A systematic review of methods to diagnose oral dryness and salivary gland function. BMC Oral Health., 12(1):29.
  9. Vernillo AT. (2001): Diabetes mellitus: Relevance to dental treatment. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 91(3):263?70.
  10. Islam NM, Bhattacharyya I, Cohen DM. (2011): Common oral manifestations of systemic disease. Otolaryngol Clin North Am., 44(1):161?82.
  11. Takagi Y, Sumi M, Van Cauteren M, Nakamura T. (2005): Fast and high-resolution MR sialography using a small surface coil. J Magn Reson Imaging., 22(1):29?37.
  12. Hugill J, Sala E, Hollingsworth KG, Lomas DJ. (2008): MR sialography: The effect of a sialogogue and ductal occlusion in volunteers. Br J Radiol., 81(967):583?6.
  13. Carda C, Mosquera-Lloreda N, Salom L, Gomez De Ferraris ME, Peydr? A, Carda DC. (2006): Structural and functional salivary disorders in type 2 diabetic patients. Med Oral Patol Oral Cir Bucal., 11:309?14.
  14. Sandberg GE, Wikblad KF. (2003): Oral dryness and peripheral neuropathy in subjects with type 2 diabetes. J Diabetes Complications., 17(4):192?8.
  15. Khovidhunkit SPS, Suwantuntula T, Thaweboon S, Mitrirattanakul S, Chomkhakhai U, Khovidhunkit W, et al. (2009): Preliminary Report Xerostomia , Hyposalivation , and Oral Microbiota in Type 2 Diabetic Patients : A Preliminary Study. J Med Assoc Thai., 92(9):1220?8.
  16. Vasconcelos ACU, Soares MSM, Almeida PC, Soares TC. (2010): Comparative study of the concentration of salivary and blood glucose in type 2 diabetic patients. J Oral Sci.,52(2):293?8.
  17. Campus G, Salem A, Uzzau S, Baldoni E, Tonolo G. (2005): Diabetes and periodontal disease: a case-control study. J Periodontol., 76(3):418?25.
  18. Taylor GW, Borgnakke WS. (2008): Periodontal disease: Associations with diabetes, glycemic control and complications. Oral Dis., 14(3):191?203.
  19. Dodds MW, Yeh CK, Johnson DA. (2000): Salivary alterations in type 2 (non-insulin-dependent) diabetes mellitus and hypertension. Community Dent Oral Epidemiol., 28(5):373?81.
  20. Lin CC, Sun SS, Kao A, Lee CC. (2002): Impaired salivary function in patients with noninsulin-dependent diabetes mellitus with xerostomia. J Diabetes Complications., 16(2):176?9.
  21. Mata AD, Marques D, Rocha S, Francisco H, Santos C, Mesquita MF, et al. Effects of diabetes mellitus on salivary secretion and its composition in the human. Mol Cell Biochem [Internet]. 2004;261(1):137?42. Available from: http://www.scopus.com/inward/record.url?eid=2-s2.0-3543149684&partnerID=40&md5=9d2781d3be599d45d702120d4a09730d%5Cnhttp://www.embase.com/search/results?subaction=viewrecord&from=export&id=L39022414%5Cnhttp://dx.doi.org/10.1023/B:MCBI.0000028748.40917.6f
  22. Montaldo L, Montaldo P, Papa A, Caramico N, Toro G. (2010): Effects of saliva substitutes on oral status in patients with Type-2 diabetes. Diabet Med., 27(11):1280?3.
  23. Ch?vez EM, Borrell LN, Taylor GW, Ship J a. (2001): A longitudinal analysis of salivary flow in control subjects and older adults with type 2 diabetes. Oral Surg Oral Med Oral Pathol Oral Radiol Endod., 91(2):166?73.
  24. Panchbhai AS, Degwekar SS, Bhowte RR. (2010): Estimation of salivary glucose, salivary amylase, salivary total protein and salivary flow rate in diabetics in India., 52(3):359?68.
  25. Al-Maskari AY, Al-Maskari MY, Al-Sudairy S. (2011): Oral manifestations and complications of diabetes mellitus: A review. Sultan Qaboos Univ Med J., 11(2):179?86.
  26. Chen S, Paul BC, Myssiorek D. (2013): An Algorithm Approach to Bilateral Parotid Enlargement Bilateral parotid disease. Otolaryngol - Head Neck Surg., 148(5):732?9.
  27. Carda C, Carranza M, Arriaga A, Diaz A, Peydro? A and G mez DF. (2005): Structural differences between alcoholic and diabetic parotid sialosis. Med Oral Patol Oral CirBucal., 10:309?14.
  28. Scully C, Bag?n J V., Eveson JW, Barnard N, Turner FM. (2008): Sialosis: 35 cases of persistent parotid swelling from two countries. Br J Oral Maxillofac Surg., 46(6):468?72.

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